The possibility of hormone-mediated PSA derangement in prostate cancer treatment

PSA Screening in Prostate Cancer

Introduction: Prostate cancer is one of the most common cancers in Iranian men. PSA(prostate specific antigen) screening is a controversial issue because PSA screening leads to diagnose of patients with low risk prostate cancer who not only do not benefit from treatment but also suffer from complication caused by treatment. On the other hand, without prostate cancer screening, the rate of meta...

psa in early diagnosis of prostate cancer

we report our experience with 124 patients were referred 70 our urology clinic in sina hospital for urinary retention. serum psa analyzed by using a monoclonal assay. all patients underwent digital rectal examination. the patients devided in 3 groups: group 1 (87 men) with a serum psa level less than 4 ng/ml, group 2 (26 men) with a serum psa level 4-10 ng/ml and group 3 (11 men) with a serum p...

Hyperthermia: a treatment possibility for prostate cancer

PSA Recurrence of Prostate Cancer:

Today, because of prostate-specific antigen (PSA) screening, prostate cancer in most patients is detected earlier and at younger ages than in the past. Despite this early detection and after definitive therapy, whether by radical prostatectomy (RP) or radiation therapy (RT), a biochemical recurrence will develop within 10 years of treatment in about 35% of men.1,2 With about 230,000 cases of pr...

Clinical Significance of Free-to-Total Prostate-Specific Antigen (PSA) Ratio in Advanced Prostate Cancer Patients with PSA Less than 0.1 ng/ml after Hormone Treatment

PURPOSE We analyzed the pattern of change in the free-to-total prostate-specific antigen (f/t PSA) ratio and the progression to castration-resistant prostate cancer (CRPC) in patients with advanced prostate cancer who received hormone treatment and whose PSA nadir was below 0.1 ng/ml. MATERIALS AND METHODS We retrospectively analyzed the medical records of 52 patients with advanced prostate c...

Treatment options in hormone resistant prostate cancer.

Prostate cancer is the most frequently diagnosed cancer in humans. An estimated 189000 men will be diagnosed with prostate cancer in the USA in 2002, and an estimated 30200 will die as a result of the disease [1]. It is predominantly diagnosed in older men and is rarely diagnosed in men under the age of 40 in contrast with the observation that microscopic prostate cancer is present in 80–100% o...